Article
The chromosome 15q14 locus for bipolar disorder and schizophrenia: is C15orf53 a major candidate gene?
Journal of psychiatric research - 1 Nov 2012
Kranz Thorsten M, Ekawardhani Savira, Lin Michelle K, Witzmann Simone R, Streit Fabian, Schuelter Ulrike, Bauer Hans, Henseler Darja, Turner Jonathan D, Muller Claude P, Reif Andreas, Schote Andrea B, Meyer Jobst
Abstract excerpt
Bipolar disorder (BD) and schizophrenia are complexly inherited and highly heritable disorders with currently unknown etiologies. Recently, two independent genome-wide association studies for BD identified a small region on chromosome 15q14-15.1, pointing to a locus close to the gene C15orf53. Previously, this genomic region was also found to co-segregate with periodic catatonia (SCZD10, OMIM %605419), an...
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