Article
Sequence, "subtle" alternative splicing and expression of the CYYR1 (cysteine/tyrosine-rich 1) mRNA in human neuroendocrine tumors.
BMC cancer - 18 Apr 2007
Vitale Lorenza, Frabetti Flavia, Huntsman Shane A, Canaider Silvia, Casadei Raffaella, Lenzi Luca, Facchin Federica, Carinci Paolo, Zannotti Maria, Coppola Domenico, Strippoli Pierluigi
Abstract excerpt
BACKGROUND: CYYR1 is a recently identified gene located on human chromosome 21 whose product has no similarity to any known protein and is of unknown function. Analysis of expressed sequence tags (ESTs) have revealed high human CYYR1 expression in cells belonging to the diffuse neuroendocrine system (DNES). These cells may be the origin of neuroendocrine (NE) tumors. The aim of this study was to conduct an...
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