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Article

Expression of the two alternatively spliced PRKAR1A RNAs in human endocrine glands.

Molecular and cellular endocrinology - 30 Jun 2005

Peverelli Erika, Mantovani Giovanna, Bondioni Sara, Pellegrini Caterina, Bosari Silvano, Lania Andrea G, Beck-Peccoz Paolo, Spada Anna

Abstract excerpt

Heterozygous loss of function mutations in human PKAR1A gene (PRKAR1A) have been identified in patients with Carney complex (CNC), an autosomal dominant familial multiple neoplasia syndrome displaying different endocrine tumors, including adrenocortical tumors, GH-secreting pituitary tumors and thyroid adenomas. Although PRKAR1A is encoded by a single gene, it is transcribed from at least two different promoters,...

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Identifiers

PMID: 15921845
DOI: 10.1016/j.mce.2005.03.015

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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