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Most C6 Cells Are Cancer Stem Cells: Evidence from Clonal and Population Analyses

15 Apr 2007

Abstract excerpt

Cancer stem cells have been isolated from human gliomas and many other parenchymal tumors. It was previously assumed that many established malignant cell lines also contain a rare subpopulation of stem cells. This study was designed to investigate the fraction of cancer stem cells in the C6 glioma cell line using clonal and population analyses, rather than isolating methods, which are based on specific markers....

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PMID: 17440081
DOI: 10.1158/0008-5472.can-06-3912

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