Large-scale pathways-based association study in amyotrophic lateral sclerosis.

doi:10.1093/brain/awm055

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Article

Large-scale pathways-based association study in amyotrophic lateral sclerosis.

Brain : a journal of neurology - 1 Sept 2007

Kasperaviciute Dalia, Weale Mike E, Shianna Kevin V, Banks Gareth T, Simpson Claire L, Hansen Valerie K, Turner Martin R, Shaw Christopher E, Al-Chalabi Ammar, Pall Hardev S, Goodall Emily F, Morrison Karen E, Orrell Richard W, Beck Marcus, Jablonka Sibylle, Sendtner Michael, Brockington Alice, Ince Paul G, Hartley Judith, Nixon Hannah, Shaw Pamela J, Schiavo Giampietro, Wood Nicholas W, Goldstein David B, Fisher Elizabeth M C

Abstract excerpt

Sporadic amyotrophic lateral sclerosis (ALS), a devastating neurodegenerative disease, most likely results from complex genetic and environmental interactions. Although a number of association studies have been performed in an effort to find genetic components of sporadic ALS, most of them resulted in inconsistent findings due to a small number of genes investigated in relatively small sample sizes, while the...

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PMID: 17439985
DOI: 10.1093/brain/awm055

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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