Article
Integrated molecular landscape of amyotrophic lateral sclerosis provides insights into disease etiology.
Brain pathology (Zurich, Switzerland) - 1 Mar 2018
Klemann C J H M, Visser J E, Van Den Bosch L, Martens G J M, Poelmans G
Abstract excerpt
Amyotrophic lateral sclerosis (ALS) is a severe, progressive and ultimately fatal motor neuron disease caused by a combination of genetic and environmental factors, but its underlying mechanisms are largely unknown. To gain insight into the etiology of ALS, we here conducted genetic network and literature analyses of the top-ranked findings from six genome-wide association studies of sporadic ALS (involving 3589...
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