Article
Fronto‐striatal dysfunction and potential compensatory mechanisms in male adolescents with fragile X syndrome
16 Apr 2007
Abstract excerpt
Response inhibition is an important facet of executive function. Fragile X syndrome (FraX), with a known genetic etiology (fragile X mental retardation-1 (FMR1) mutation) and deficits in response inhibition, may be an ideal condition for elucidating interactions among gene-brain-behavior relationships. Functional magnetic resonance imaging (fMRI) studies have shown evidence of aberrant neural activity when...
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