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Article

A simple and improved correction for population stratification in case-control studies.

American journal of human genetics - 1 May 2007

Epstein Michael P, Allen Andrew S, Satten Glen A

Abstract excerpt

Population stratification remains an important issue in case-control studies of disease-marker association, even within populations considered to be genetically homogeneous. Campbell et al. (Nature Genetics 2005;37:868-872) illustrated this by showing that stratification induced a spurious association between the lactase gene (LCT) and tall/short status in a European American sample. Furthermore, existing...

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Identifiers

PMID: 17436246
DOI: 10.1086/516842
PMCID: PMC1852732

Genes

LCT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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