Article
Investigation of parent-of-origin effects in ADHD candidate genes.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Sept 2007
Kim Jang Woo, Waldman Irwin D, Faraone Stephen V, Biederman Joseph, Doyle Alysa E, Purcell Shaun, Arbeitman Lori, Fagerness Jesen, Sklar Pamela, Smoller Jordan W
Abstract excerpt
Attention deficit hyperactivity disorder (ADHD) is a common early-onset childhood disorder with a strong genetic component. Results from previous studies have suggested that there may be a parent-of-origin effect for ADHD candidate genes. In particular, a recent investigation identified a pattern of paternal over-transmission of risk alleles for nine ADHD candidate genes. We examined this phenomenon in a sample...
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