Article
High-fat diets: modeling the metabolic disorders of human obesity in rodents.
Obesity (Silver Spring, Md.) - 1 Apr 2007
Buettner Roland, Schölmerich Jürgen, Bollheimer L Cornelius
Abstract excerpt
RESEARCH METHODS AND PROCEDURES: High-fat (HF) diet feeding can induce obesity and metabolic disorders in rodents that resemble the human metabolic syndrome. However, this dietary intervention is not standardized, and the HF-induced phenotype varies distinctly among different studies. The question which HF diet type is best to model the metabolic deterioration seen in human obesity remains unclear. Therefore, in...
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