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Article

Obesity-Resistant Mice on a High-Fat Diet Display a Distinct Phenotype Linked to Enhanced Lipid Metabolism.

Nutrients - 4 Jan 2024

Milhem Fadia, Skates Emily, Wilson Mickey, Komarnytsky Slavko

Abstract excerpt

Individually, metabolic variations can significantly influence predisposition to obesity in the form of the obesity-prone (super-responders) and obesity-resistant (non-responders) phenotypes in response to modern calorie-dense diets. In this study, C57BL/6J mice (n = 76) were randomly assigned to either a low-fat diet (LFD) or a high-fat diet (HFD) for 6 weeks, followed by selection of the normally obese (HFD),...

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Identifiers

PMID: 38202000
DOI: 10.3390/nu16010171
PMCID: PMC10780630

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