Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Apolipoprotein E polymorphism, homocysteine serum levels and hippocampal volume in patients with alcoholism: an investigation of a gene-environment interaction.

The pharmacogenomics journal - 1 Apr 2008

Wilhelm J, Frieling H, von Ahsen N, Hillemacher T, Kornhuber J, Bleich S

Abstract excerpt

There is growing evidence that disadvantageous influences of the apolipoprotein E4 allele in the central nervous system are modified by environmental and dietary conditions. The present study investigated the gene-environment interaction of apolipoprotein E4 with homocysteine serum levels in patients with alcohol dependence with regard to alcohol-related hippocampal volume loss using volumetric high-resolution...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alcoholism
Share to Apolipoprotein E4

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Environment

Share to Hippocampus

Share to Homocysteine

Share to Hyperhomocysteinemia

Share to Magnetic Resonance Imaging

Share to Organ Size

Source

Identifiers

PMID: 17420762
DOI: 10.1038/sj.tpj.6500453

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 9 closest

Apolipoprotein E polymorphism, homocysteine serum levels and hippocampal volume in patients with alcoholism: an investigation of a gene-environment interaction.PMID 17420762Read ↗

Apolipoprotein E genotype modulates effects of vitamin B12 and homocysteine on grey matter volume in Alzheimer's disease.Semantic proximity Read ↗

Apolipoprotein E epsilon 4 is associated with hippocampal volume reduction in females with alcoholism.Semantic proximity Read ↗

Independent and combined effects of methamphetamine use disorders and APOEε4 allele on cognitive performance and brain morphometry.Semantic proximity Read ↗

Genetic and behavioral determinants of hippocampal volume recovery during abstinence from alcohol.Semantic proximity Read ↗

The effect of apolipoprotein polymorphism on brain in mild cognitive impairment: a voxel-based morphometric study.Semantic proximity Read ↗

Synergistic effects of the dopaminergic and glutamatergic system on hippocampal volume in alcohol-dependent patients.Semantic proximity Read ↗

Alterations in homocysteine metabolism among alcohol dependent patients--clinical, pathobiochemical and genetic aspects.Semantic proximity Read ↗

Significant impact of MTHFR C677T polymorphism on plasma homovanillic acid (HVA) levels among alcohol-dependent patients.Semantic proximity Read ↗

Effect of apolipoprotein ε4 allele on hippocampal and brain volume in intractable temporal lobe epilepsy.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.