Article
Temperamental fearfulness in childhood and the serotonin transporter promoter region polymorphism: a multimethod association study.
Psychiatric genetics - 1 Jun 2007
Hayden Elizabeth P, Dougherty Lea R, Maloney Bryan, Emily Durbin C, Olino Thomas M, Nurnberger John I, Lahiri Debomoy K, Klein Daniel N
Abstract excerpt
OBJECTIVES: Early-emerging, temperamental differences in fear-related traits may be a heritable vulnerability factor for anxiety disorders. Previous research indicates that the serotonin transporter promoter region polymorphism is a candidate gene for such traits. METHODS: Associations between 5-HTTLPR genotype and indices of fearful child temperament, derived from maternal report and standardized laboratory...
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