Article
Serotonin receptor genes 5HT1A and 5HT2A modify the relation between childhood temperament and adulthood hostility.
Genes, brain, and behavior - 1 Feb 2008
Keltikangas-Järvinen L, Puttonen S, Kivimäki M, Elovainio M, Pulkki-Råback L, Koivu M, Rontu R, Lehtimäki T
Abstract excerpt
We examined a modifying role of 5HT1A and 5HT2A receptors in the relation between childhood difficult temperament and adulthood hostility in 729 subjects derived from a population-based sample. Subjects were 3-12 years when their childhood temperaments consisting of hyperactivity, low sociability and negative emotionality (i.e. the difficult temperament), were assessed by their mothers. Their adulthood hostility...
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