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Article

Negative emotionality mediates the association of 5-HTTLPR genotype and depression in children with and without ADHD.

Psychiatry research - 30 Jan 2014

Li James J, Lee Steve S

Abstract excerpt

The 44-base-pair polymorphism in the promoter region of the serotonin transporter gene (5-HTTLPR) has been implicated in the etiology of depression, but relatively little is known about potential mediators of this association. Although dimensions of temperament are likely to be proximal to the neurobiological and genetic factors underlying depression, studies have yet to formally evaluate temperament as a...

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Identifiers

PMID: 24287203
DOI: 10.1016/j.psychres.2013.10.026

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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