Article
Serotonin transporter polymorphism moderates effects of prenatal maternal anxiety on infant negative emotionality.
Biological psychiatry - 15 Mar 2011
Pluess Michael, Velders Fleur P, Belsky Jay, van IJzendoorn Marinus H, Bakermans-Kranenburg Marian J, Jaddoe Vincent W V, Hofman Albert, Arp Pascal P, Verhulst Frank C, Tiemeier Henning
Abstract excerpt
BACKGROUND: Consistent with the fetal programming hypothesis, effects of maternal prenatal anxiety have been found to predict various measures of infant temperament in the early postnatal period. In recent years, a polymorphism in the serotonin transporter gene (5-HTTLPR) emerged as a moderator of diverse environmental influences on different outcomes, with individuals carrying the short allele being generally...
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