Prenatal molecular diagnosis of inherited cholestatic diseases.

Abstract excerpt

OBJECTIVES: Progressive familial intrahepatic cholestasis (PFIC) and to a lesser extent, Alagille syndrome, often lead to end-stage liver disease during childhood. We report our experience of DNA-based prenatal diagnosis of PFIC1-3 and Alagille syndrome. PATIENTS AND METHODS: Four molecular antenatal diagnoses were performed in 3 PFIC families and 17 in 11 Alagille syndrome families. DNA was isolated from...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Alagille Syndrome
• Share to Cholestasis, Intrahepatic