Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Prospective Screening for Pediatric Mitochondrial Trifunctional Protein Defects in Pregnancies Complicated by Liver Disease

6 Nov 2002

Abstract excerpt

CONTEXT: Acute fatty liver of pregnancy (AFLP) and hemolysis, elevated liver enzymes, and low platelets (HELLP) syndrome are serious complications of pregnancy. Studies in families with recessively inherited mitochondrial trifunctional protein defects documented an association between these maternal illnesses and fetal deficiency of long-chain 3-hydroxyacyl coenzyme A dehydrogenase; this enzyme resides in the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Metabolism and Genetic Disorders
Share to Mitochondrial Function and Pathology
Share to Neonatal Health and Biochemistry

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 12413376
DOI: 10.1001/jama.288.17.2163

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Prospective Screening for Pediatric Mitochondrial Trifunctional Protein Defects in Pregnancies Complicated by Liver DiseasePMID 12413376Read ↗

A fetal fatty-acid oxidation disorder as a cause of liver disease in pregnant women.Semantic proximity Read ↗

Maternal heterozygosity for a mitochondrial trifunctional protein mutation as a cause for liver disease in pregnancy.Semantic proximity Read ↗

Fetal genotypes and pregnancy outcomes in 35 families with mitochondrial trifunctional protein mutations.Semantic proximity Read ↗

Maternal acute fatty liver of pregnancy associated with fetal trifunctional protein deficiency: molecular characterization of a novel maternal mutant allele.Semantic proximity Read ↗

Molecular prenatal diagnosis in families with fetal mitochondrial trifunctional protein mutations.Semantic proximity Read ↗

Liver disease in pregnancy and fetal fatty acid oxidation defects.Semantic proximity Read ↗

Neither maternal nor fetal mutation (E474Q) in the alpha-subunit of the trifunctional protein is frequent in pregnancies complicated by HELLP syndrome.Semantic proximity Read ↗

Acute fatty liver of pregnancy associated with fetal mitochondrial trifunctional protein deficiency.Semantic proximity Read ↗

Acute fatty liver disease of pregnancySemantic proximity Read ↗

Acute Fatty Liver Disease of Pregnancy: Updates in Pathogenesis, Diagnosis, and ManagementSemantic proximity Read ↗

The molecular basis of pediatric long chain 3-hydroxyacyl-CoA dehydrogenase deficiency associated with maternal acute fatty liver of pregnancy.Semantic proximity Read ↗

Mitochondrial Dysfunction and Acute Fatty Liver of PregnancySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.