Article
A longitudinal study to identify laboratory predictors of liver disease outcome in Alagille syndrome.
Journal of pediatric gastroenterology and nutrition - 1 May 2010
Kamath Binita M, Munoz Pedro S, Bab Natalie, Baker Alastair, Chen Zhongxue, Spinner Nancy B, Piccoli David A
Abstract excerpt
OBJECTIVES: Liver disease in Alagille syndrome (AGS) is highly variable, ranging from biochemical abnormalities only to end-stage disease. It is not possible to predict whether a child with cholestasis will have improvement or progression of liver disease. This poses a challenge to the clinician in terms of timing therapies. The study aim was to identify laboratory markers present in children younger than 5 years...
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