Article
CARD15 status and familial predisposition for Crohn's disease and colonic gene expression.
Digestive diseases and sciences - 1 Aug 2007
Csillag Claudio, Nielsen Ole Haagen, Borup Rehannah, Olsen Jørgen, Bjerrum Jacob Tveiten, Nielsen Finn Cilius
Abstract excerpt
Familial disposition and mutations in the Caspase Recruitment Domain 15 (CARD15) have been associated with an increased risk for Crohn's disease (CD). This study investigated whether these risk factors correlate with colonic gene expression profiles generated by DNA-microarray technology. Tissue specimens from descending colon were obtained during colonoscopy from 45 CD patients (18 from areas with inflammation...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
