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Article

Salmonella typhimurium lacking ribose chemoreceptors localize in tumor quiescence and induce apoptosis.

Cancer research - 1 Apr 2007

Kasinskas Rachel W, Forbes Neil S

Abstract excerpt

The effectiveness of most chemotherapeutics is limited by their inability to penetrate deep into tumor tissue and their ineffectiveness against quiescent cells. Motile Salmonella typhimurium, which are specifically attracted to compounds produced by quiescent cancer cells, could overcome this therapeutic barrier. We hypothesized that individual chemoreceptors target S. typhimurium to specific tumor...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 17409428
DOI: 10.1158/0008-5472.CAN-06-2618

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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