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Article

Herpes simplex virus latency-associated transcript sequence downstream of the promoter influences type-specific reactivation and viral neurotropism.

Journal of virology - 1 Jun 2007

Bertke Andrea S, Patel Amita, Krause Philip R

Abstract excerpt

Herpes simplex virus (HSV) establishes latency in sensory nerve ganglia during acute infection and may later periodically reactivate to cause recurrent disease. HSV type 1 (HSV-1) reactivates more efficiently than HSV-2 from trigeminal ganglia while HSV-2 reactivates more efficiently than HSV-1 from lumbosacral dorsal root ganglia (DRG) to cause recurrent orofacial and genital herpes, respectively. In a previous...

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Identifiers

PMID: 17409161
DOI: 10.1128/JVI.02701-06
PMCID: PMC1900114

Genes

LAT

Provenance

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Source receipt: pubmed, retrieved 7 Sept 2026.

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Herpes simplex virus latency-associated transcript sequence downstream of the promoter influences type-specific reactivation and viral neurotropism.PMID 17409161Read ↗

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