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Article

Herpes simplex virus type 1 latency-associated transcription unit promotes anatomical site-dependent establishment and reactivation from latency.

Journal of virology - 1 Apr 1992

Sawtell N M, Thompson R L

Abstract excerpt

Defined herpes simplex virus type 1 (HSV-1) mutants KOS/1 and KOS/62 (positive and negative, respectively, for latency-associated transcripts [LATs]) express the Escherichia coli beta-galactosidase (beta-Gal) gene during latency. These mutants were employed to assess the functions of the latency-associated transcription unit on establishment and maintenance of and reactivation from the latent state. It was found...

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Identifiers

PMID: 1312626
DOI: 10.1128/JVI.66.4.2157-2169.1992
PMCID: PMC289008

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Source receipt: pubmed, retrieved 7 Sept 2026.

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