Article
Cloning, mapping and association studies of the ovine ABCG2 gene with facial eczema disease in sheep.
Animal genetics - 1 Apr 2007
Duncan E J, Dodds K G, Henry H M, Thompson M P, Phua S H
Abstract excerpt
Facial eczema (FE) is a hepatogenous mycotoxicosis in sheep caused by the fungal toxin sporidesmin. Resistance to FE is a multigenic trait. To identify QTL associated with this trait, a scan of ovine chromosomes was implemented. In addition, ABCG2 was investigated as a possible positional candidate gene because of its sequence homology to the yeast PDR5 protein and its functional role as a xenobiotic transporter....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
