Article
Catalase gene is associated with facial eczema disease resistance in sheep.
Animal genetics - 1 Aug 1999
Phua S H, Dodds K G, Morris C A, Paterson K A, McEwan J C, Garmonsway H G, Towers N R, Crawford A M
Abstract excerpt
Facial eczema (FE) is a hepatogenous photosensitization disease of ruminant animals, particularly in sheep which vary widely in their susceptibility to the disease. The liver damage is caused by the mycotoxin, sporidesmin. There is evidence that the toxicity of sporidesmin is due to its ability to generate 'active oxygen' species. We evaluated the catalase gene, which encodes an enzyme with antioxidant functions,...
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