Article
Effects of transplantation with bone marrow-derived mesenchymal stem cells modified by Survivin on experimental stroke in rats.
Journal of translational medicine - 6 Jul 2011
Liu Nan, Zhang Yixian, Fan Lin, Yuan Mingzhou, Du Houwei, Cheng Ronghua, Liu Deshan, Lin Feifei
Abstract excerpt
BACKGROUND: This study was performed to determine whether injury induced by cerebral ischemia could be further improved by transplantation with bone marrow-derived mesenchymal stem cells (MSCs) modified by Survivin (SVV). METHODS: MSCs derived from bone marrow of male Sprague-Dawley rats were infected by the self-inactive lentiviral vector GCFU carrying green fluorescent protein (GFP) gene and SVV recombinant...
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