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Article

Intravenous multipotent adult progenitor cell treatment decreases inflammation leading to functional recovery following spinal cord injury.

Scientific reports - 19 Nov 2015

DePaul Marc A, Palmer Marc, Lang Bradley T, Cutrone Rochelle, Tran Amanda P, Madalena Kathryn M, Bogaerts Annelies, Hamilton Jason A, Deans Robert J, Mays Robert W, Busch Sarah A, Silver Jerry

Abstract excerpt

Following spinal cord injury (SCI), immune-mediated secondary processes exacerbate the extent of permanent neurological deficits. We investigated the capacity of adult bone marrow-derived stem cells, which exhibit immunomodulatory properties, to alter inflammation and promote recovery following SCI. In vitro, we show that human multipotent adult progenitor cells (MAPCs) have the ability to modulate macrophage...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26582249
DOI: 10.1038/srep16795
PMCID: PMC4652166

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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