Article
A focus reduction neutralization assay for hepatitis C virus neutralizing antibodies.
Virology journal - 30 Mar 2007
Fournier Carole, Duverlie Gilles, François Catherine, Schnuriger Aurelie, Dedeurwaerder Sarah, Brochot Etienne, Capron Dominique, Wychowski Czeslaw, Thibault Vincent, Castelain Sandrine
Abstract excerpt
BACKGROUND/AIM: The role of humoral immunity in hepatitis C virus (HCV) infection is poorly understood. Nevertheless, there is increasing interest in characterizing the neutralizing antibodies in the serum of HCV-infected patients. Focus reduction assays have been widely used to evaluate neutralizing antibody responses against a range of non-cytopathic viruses. Based on the recent development of a HCV cell...
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