Article
SDE5, the putative homologue of a human mRNA export factor, is required for transgene silencing and accumulation of trans-acting endogenous siRNA.
The Plant journal : for cell and molecular biology - 1 Apr 2007
Hernandez-Pinzon Inmaculada, Yelina Nataliya E, Schwach Frank, Studholme David J, Baulcombe David, Dalmay Tamas
Abstract excerpt
Post-transcriptional gene silencing (PTGS) is a sequence-specific RNA degradation process conserved in fungi, plants and animals. The trigger of the mechanism is double-stranded RNA derived from transgenic or endogenous loci and formed by intra- or inter-molecular interactions of single-stranded RNAs or the action of RNA-dependent RNA polymerases (RDRs). Double-stranded RNA from various sources is processed by...
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