Familial hemiplegic migraine.

Abstract excerpt

Familial hemiplegic migraine (FHM) is a rare and genetically heterogeneous autosomal dominant subtype of migraine with aura. Mutations in the genes CACNA1A and SCNA1A, encoding the pore-forming alpha(1) subunits of the neuronal voltage-gated Ca2+ channels Ca(V)2.1 and Na+ channels Na(V)1.1, are responsible for FHM1 and FHM3, respectively, whereas mutations in ATP1A2, encoding the alpha2 subunit of the Na+, K+...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Calcium Channels
• Share to Migraine with Aura
• Share to Models, Biological