Article
Changes in Toll-like receptor (TLR)-2 and TLR4 expression and function but not polymorphisms are associated with acute anterior uveitis.
Investigative ophthalmology & visual science - 1 Apr 2007
Chang John H, Hampartzoumian Taline, Everett Beth, Lloyd Andrew, McCluskey Peter J, Wakefield Denis
Abstract excerpt
PURPOSE: To investigate the expression and polymorphisms of Toll-like receptor (TLR)-2 and -4 in the peripheral neutrophils and monocytes of patients with acute anterior uveitis (AAU). METHODS: Nine patients with active AAU and nine age- and sex-matched healthy control subjects were studied. TLR2 and -4 protein expression on CD16(+) neutrophils and CD14(+) monocytes were studied by flow cytometry. TLR function...
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