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Article

Polymorphisms in Toll-like receptors 2 and 4 genes and their expression in chronic suppurative otitis media.

Auris, nasus, larynx - 1 Dec 2015

Jotic Ana, Jesic Snezana, Zivkovic Maja, Tomanovic Nada, Kuveljic Jovana, Stankovic Aleksandra

Abstract excerpt

OBJECTIVE: Toll-like receptors (TLRs) have a prominent role in inducing innate immune response. It has been suggested that regulation of TLRs is involved in the pathogenesis of chronic otitis media. TLR 2 and TLR 4 polymorphisms were connected with susceptibility to acute otitis and chronic otitis with effusion. The objective of this study was to establish expression of TLR 2 and 4 on middle ear mucosa in...

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Identifiers

PMID: 26055429
DOI: 10.1016/j.anl.2015.04.010

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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