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Article

GNAS1 T393C polymorphism is associated with migraine.

Cephalalgia : an international journal of headache - 1 May 2007

Oterino A, Ruiz-Alegría C, Castillo J, Valle N, Bravo Y, Cayón A, Alonso A, Tejera P, Ruiz-Lavilla N, Muñoz P, Pascual J

Abstract excerpt

Migraineurs have an interictal sympathetic nervous system (SNS) hypofunctionality and hypersensitivity to adrenergic amines. The GNAS1 T393C polymorphism has been associated with a distinct SNS sensitivity in healthy subjects. We tested GNAS1 T393C variant in two independent sets of subjects. In the case-control subset, 365 migraine patients [194 with aura (MA)] vs. 347 healthy controls were studied. A...

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Identifiers

PMID: 17388805
DOI: 10.1111/j.1468-2982.2007.01305.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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