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Article

Role of TGF-β pathway polymorphisms in sporadic thoracic aortic aneurysm: rs900 TGF-β2 is a marker of differential gender susceptibility.

Mediators of inflammation - 1 Jan 2014

Scola Letizia, Di Maggio Federica M, Vaccarino Loredana, Bova Manuela, Forte Giusy I, Pisano Calogera, Candore Giuseppina, Colonna-Romano Giuseppina, Lio Domenico, Ruvolo Giovanni, Balistreri Carmela R

Abstract excerpt

Thoracic aortic aneurysm (TAA) is a progressive disorder involving gradual dilation of ascending and/or descending thoracic aorta with dissection or rupture as complications. It occurs as sporadic or defined syndromes/familial forms.Genetic, molecular and cellular mechanims of sporadic TAA forms are poorly characterized and known. Thus, our interest has been focused on investigating the role of genetic variants...

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Identifiers

PMID: 24707114
DOI: 10.1155/2014/165758
PMCID: PMC3953613

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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