Article
Monitoring patients with chronic myeloid leukemia receiving Abl tyrosine kinase inhibitor therapy.
Clinical lymphoma & myeloma - 1 Mar 2007
Oehler Vivian, Radich Jerald P
Abstract excerpt
The tyrosine kinase inhibitor (TKI) imatinib has revolutionized the treatment of chronic myeloid leukemia (CML). Complete cytogenetic remissions are standard for patients treated in chronic phase; however, treatment outcomes in advanced-phase disease are far less promising. Because hematopoietic cell transplantation is potentially curative in CML and newer TKIs are now available, the use of imatinib necessitates...
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