Article
Monitoring chronic myelogenous leukemia in the age of tyrosine kinase inhibitors.
Journal of the National Comprehensive Cancer Network : JNCCN - 1 May 2007
Radich Jerald P, Oehler Vivian
Abstract excerpt
Tyrosine kinase inhibitors (TKIs) are now standard up-front therapy for chronic myeloid leukemia (CML). Patients with newly diagnosed chronic-phase CML treated with the TKI imatinib mesylate typically experience a complete cytogenetic remission. Outcomes for patients with advanced-phase disease are distinctly worse. Unfortunately, a small proportion of chronic-phase patients experience relapse during this...
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