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Article

HIV-1 infection of human fetal thymocytes.

Journal of acquired immune deficiency syndromes - 1 Jan 1992

Tanaka K E, Hatch W C, Kress Y, Soeiro R, Calvelli T, Rashbaum W K, Rubinstein A, Lyman W D

Abstract excerpt

Some neonates with congenital human immunodeficiency virus type 1 (HIV-1) infection exhibit immune dysregulation. This suggests that fetal CD4+ cells, possibly thymocytes, may be infected during gestation. If thymocytes are infected, this may result in a disruption of T-cell differentiation. To examine this hypothesis, normal human fetal thymocytes were established in tissue culture, characterized, and then...

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Source

Identifiers

PMID: 1738092

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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