Article
Polymorphisms in the APOA1/C3/A4/A5 gene cluster and cholesterol responsiveness to dietary change.
Clinical chemistry and laboratory medicine - 1 Jan 2007
Hubacek Jaroslav A, Bohuslavova Romana, Skodova Zdena, Pitha Jan, Bobkova Dagmar, Poledne Rudolf
Abstract excerpt
BACKGROUND: The relationship between dietary composition and plasma lipids is to some extent genetically determined. It has been found that variants of some genes (e.g., apolipoprotein E and cholesterol 7-alpha hydroxylase) play an important role in changes in plasma lipid levels in response to dietary intervention. We analyzed the effect of variation in the apolipoprotein (APO) APOA1/C3/A4/A5 gene cluster on...
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