Article
Population pharmacokinetics of the BEACOPP polychemotherapy regimen in Hodgkin's lymphoma and its effect on myelotoxicity.
Clinical pharmacokinetics - 1 Jan 2007
Wilde Stefan, Jetter Alexander, Rietbrock Stephan, Kasel Dirk, Engert Andreas, Josting Andreas, Klimm Beate, Hempel Georg, Reif Stefanie, Jaehde Ulrich, Merkel Ute, Busse Dagmar, Schwab Matthias, Diehl Volker, Fuhr Uwe
Abstract excerpt
BACKGROUND AND OBJECTIVE: The BEACOPP (bleomycin, etoposide, doxorubicin, cyclophosphamide, vincristine, procarbazine and prednisone) chemotherapy regimen for the treatment of advanced Hodgkin's lymphoma has a superior outcome, but its toxicity (mainly haematotoxicity) is pronounced and highly va...
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