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Article

Dose calculation of anticancer drugs.

Expert opinion on drug metabolism & toxicology - 1 Oct 2008

Gao Bo, Klumpen Heinz-Josef, Gurney Howard

Abstract excerpt

BACKGROUND: Anticancer drugs are characterized by a narrow therapeutic window and significant inter-patient variability in therapeutic and toxic effects. Current body surface area (BSA)-based dosing fails to standardize systemic anticancer drug exposure and other alternative dosing strategies also have their limitations. Just as important as the initial dose selection is the subsequent dose revision to ensure the...

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PMID: 18798700
DOI: 10.1517/17425255.4.10.1307

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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