Article
Vaccine efficacy of an attenuated but persistent Mycobacterium tuberculosis cysH mutant.
Journal of medical microbiology - 1 Apr 2007
Senaratne Ryan H, Mougous Joseph D, Reader J Rachel, Williams Spencer J, Zhang Tianjiao, Bertozzi Carolyn R, Riley Lee W
Abstract excerpt
The emergence of drug-resistant Mycobacterium tuberculosis strains and the widespread occurrence of AIDS demand newer and more efficient control of tuberculosis. The protective efficacy of the current Mycobacterium bovis bacille Calmette-Guérin (BCG) vaccine is highly variable. Therefore, development of an effective new vaccine has gained momentum in recent years. Recently, several M. tuberculosis mutants were...
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