Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Vaccine potential of attenuated mutants of Corynebacterium pseudotuberculosis in sheep.

Infection and immunity - 1 Feb 1998

Simmons C P, Dunstan S J, Tachedjian M, Krywult J, Hodgson A L, Strugnell R A

Abstract excerpt

Corynebacterium pseudotuberculosis, a gram-positive facultative intracellular bacterial pathogen, is the etiological agent of the economically important disease caseous lymphadenitis (CLA) in both sheep and goats. Attenuated mutants of C. pseudotuberculosis have the potential to act as novel vaccines against CLA and as veterinary vaccine vectors. In this report, we have assessed the virulence of both aroQ and pld...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antibodies, Bacterial
Share to Bacterial Vaccines
Share to Hydro-Lyases

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Immunoglobulin G

Share to Mutation

Share to Vaccination

Share to Vaccines, Attenuated

Source

Open in PubMed Open full text

Identifiers

PMID: 9453598
DOI: 10.1128/IAI.66.2.474-479.1998
PMCID: PMC107930

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Vaccine potential of attenuated mutants of Corynebacterium pseudotuberculosis in sheep.PMID 9453598Read ↗

Attenuation and vaccine potential of aroQ mutants of Corynebacterium pseudotuberculosis.Semantic proximity Read ↗

Antigens of<i>Corynebacterium pseudotuberculosis</i>and prospects for vaccine developmentSemantic proximity Read ↗

Corynebacterium pseudotuberculosis: microbiology, biochemical properties, pathogenesis and molecular studies of virulence.Semantic proximity Read ↗

Rational attenuation of Corynebacterium pseudotuberculosis: potential cheesy gland vaccine and live delivery vehicleSemantic proximity Read ↗

Efficacy of an ovine caseous lymphadenitis vaccine formulated using a genetically inactive form of the Corynebacterium pseudotuberculosis phospholipase DSemantic proximity Read ↗

Putative virulence factors of Corynebacterium pseudotuberculosis FRC41: vaccine potential and protein expressionSemantic proximity Read ↗

Corynebacterium pseudotuberculosis: Immunological Responses in Animal Models and Zoonotic PotentialSemantic proximity Read ↗

Targeted mutagenesis of the phospholipase D gene results in decreased virulence of Corynebacterium pseudotuberculosis.Semantic proximity Read ↗

Corynebacterium pseudotuberculosis cp09 mutant and cp40 recombinant protein partially protect mice against caseous lymphadenitis.Semantic proximity Read ↗

An iron-acquisition-deficient mutant of Corynebacterium pseudotuberculosis efficiently protects mice against challenge.Semantic proximity Read ↗

Identification of new Corynebacterium pseudotuberculosis antigens by immunoscreening of gene expression librarySemantic proximity Read ↗

Residual virulence and immunogenicity of CGV26 and CGV2631 B. melitensis Rev. 1 deletion mutant strains in sheep after subcutaneous or conjunctival vaccination.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.