Article
Androgen receptor gene CAG trinucleotide repeats in anovulatory infertility and polycystic ovaries.
The Journal of clinical endocrinology and metabolism - 1 Sept 2000
Mifsud A, Ramirez S, Yong E L
Abstract excerpt
Hyperandrogenism is currently thought to be central to the pathogenesis of polycystic ovarian syndrome (PCOS), a common endocrine disorder in premenopausal women characterized by irregular menstruation and anovulatory infertility. Although hyperandrogenism is characteristic, some women with PCOS have normal serum androgen levels. All androgens act through the X-linked androgen receptor (AR), the N-terminal domain...
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