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Comparative functional analysis of the lac operons in Streptococcus pyogenes

19 Mar 2007

Abstract excerpt

Having no known environmental reservoir, Streptococcus pyogenes, a bacterium responsible for a wider variety of human diseases than any other bacterial species, must rely on its host for metabolic substrates. Although a streptococcal aldolase, LacD.1, has been adapted to virulence gene regulation, both LacD.1 and a paralogous protein, LacD.2, are predicted to function in the tagatose 6-phosphate pathway for...

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PMID: 17371500
DOI: 10.1111/j.1365-2958.2007.05663.x

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