Article
Zebrafish as a new model for phenotype-based screening of melanogenic regulatory compounds.
Pigment cell research - 1 Apr 2007
Choi Tae-Young, Kim Jin-Hwa, Ko Dong Han, Kim Cheol-Hee, Hwang Jae-Sung, Ahn Soomi, Kim Sun Yeou, Kim Chang-Deok, Lee Jeung-Hoon, Yoon Tae-Jin
Abstract excerpt
Although many hypo-pigmenting agents are currently available, the demand for novel whitening agents is increasing, in part due to the weak effectiveness and unwanted side effects of currently available compounds. To screen for novel hypo-pigmenting agents, many methodologies such as cell culture and enzymatic assays are routinely used. However, these models have disadvantages in terms of physiological and...
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