Article
Interference Potential of Tannins and Chlorophylls in Zebrafish Phenotypic-Based Assays.
Assay and drug development technologies - 1 Oct 2018
Samat Norazwana, Ng Mei Fong, Ruslan Nur Faizah, Okuda Kazuhide Shaun, Tan Pei Jean, Patel Vyomesh
Abstract excerpt
Natural products are prolific producers of diverse chemical scaffolds, which have yielded several clinically useful drugs. However, the complex features of natural products present challenges for identifying bioactive molecules using high-throughput screens. For most assays, measured endpoints are either colorimetric or luminescence based. Thus, the presence of the major metabolites, tannins, and chlorophylls, in...
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