Article
A Drosophila adenosine receptor activates cAMP and calcium signaling.
Insect biochemistry and molecular biology - 1 Apr 2007
Dolezelova Eva, Nothacker Hans-Peter, Civelli Olivier, Bryant Peter J, Zurovec Michal
Abstract excerpt
Adenosine receptors (AdoR) are members of the G protein-coupled receptor superfamily and mediate extracellular adenosine signaling, but the mechanism of adenosine signaling is still unclear. Here we report the first characterization of an insect AdoR, encoded by the Drosophila gene CG9753. Adenosine stimulation of Chinese hamster ovary cells carrying transiently expressed CG9753 led to a dose-dependent increase...
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