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Article

Medaka dmY/dmrt1Y is not the universal primary sex-determining gene in fish.

Trends in genetics : TIG - 1 Apr 2003

Volff Jean-Nicolas, Kondo Mariko, Schartl Manfred

Abstract excerpt

An outstanding candidate for a primary male-determining gene equivalent to Sry of mammals has been recently described from a non-mammalian vertebrate, the medaka fish (Oryzias latipes). However, the universality of dmY/dmrt1Y as the master sex-determining gene in fish is questionable. Phylogenetic analysis shows that dmY/dmrt1Y is an evolutionarily young Y chromosome-specific duplicate of a gene involved in...

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Source

Identifiers

PMID: 12683972
DOI: 10.1016/S0168-9525(03)00051-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

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Medaka dmY/dmrt1Y is not the universal primary sex-determining gene in fish.PMID 12683972Read ↗

Sex determination in fish: Lessons from the sex-determining gene of the teleost medaka, Oryzias latipes.Semantic proximity Read ↗

DMY gene induces male development in genetically female (XX) medaka fish.Semantic proximity Read ↗

DMY is a Y-specific DM-domain gene required for male development in the medaka fish.Semantic proximity Read ↗

Cloning of the dmrt1 gene of Xiphophorus maculatus: dmY/dmrt1Y is not the master sex-determining gene in the platyfish.Semantic proximity Read ↗

Sex determination, gonadal sex differentiation, and plasticity in vertebrate speciesSemantic proximity Read ↗

Evolution of DMY, a newly emergent male sex-determination gene of medaka fish.Semantic proximity Read ↗

Dmrt1 mutation causes a male-to-female sex reversal after the sex determination by Dmy in the medaka.Semantic proximity Read ↗

Two DM domain genes, <i>DMY</i> and <i>DMRT1</i>, involved in testicular differentiation and development in the medaka, <i>Oryzias latipes</i>Semantic proximity Read ↗

The Y chromosome that lost the male-determining function behaves as an X chromosome in the medaka fish, Oryzias latipes.Semantic proximity Read ↗

Evolution of the sex-determining gene in the teleostean genus Oryzias.Semantic proximity Read ↗

Oryzias curvinotus Has<i>DMY</i>, a Gene That Is Required for Male Development in the Medaka, O. latipesSemantic proximity Read ↗

A duplicated copy of <i>DMRT1</i> in the sex-determining region of the Y chromosome of the medaka, <i>Oryzias latipes</i>Semantic proximity Read ↗

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