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Article

Variation in GYS1 interacts with exercise and gender to predict cardiovascular mortality.

PloS one - 14 Mar 2007

Fredriksson Jenny, Anevski Dragi, Almgren Peter, Sjögren Marketa, Lyssenko Valeriya, Carlson Joyce, Isomaa Bo, Taskinen Marja-Riitta, Groop Leif, Orho-Melander Marju

Abstract excerpt

BACKGROUND: The muscle glycogen synthase gene (GYS1) has been associated with type 2 diabetes (T2D), the metabolic syndrome (MetS), male myocardial infarction and a defective increase in muscle glycogen synthase protein in response to exercise. We addressed the questions whether polymorphism in GYS1 can predict cardiovascular (CV) mortality in a high-risk population, if this risk is influenced by gender or...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 17356695
DOI: 10.1371/journal.pone.0000285
PMCID: PMC1805686

Genes

GYS1
APOE

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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