Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association of muscle glycogen synthase polymorphism with insulin resistance in type 2 diabetic patients.

Metabolism: clinical and experimental - 1 Jul 2003

Motoyama Koka, Emoto Masanori, Tahara Hideki, Komatsu Miyoko, Shoji Tetsuo, Inaba Masaaki, Nishizawa Yoshiki

Abstract excerpt

The aim of the present study is to investigate whether Met416Val (M416V) polymorphism of glycogen synthase (GYS1) gene is associated with insulin resistance in type 2 diabetes. In 100 type 2 diabetic subjects (66 men and 34 women), the M416V polymorphism of GYS1 gene was analyzed by polymerase ch...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Blood Glucose
Share to Glucose Clamp Technique
Share to Glycated Hemoglobin

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Glycogen Synthase

Share to Insulin

Share to Insulin Resistance

Share to Muscle, Skeletal

Share to Regression Analysis

Source

Identifiers

PMID: 12870167
DOI: 10.1016/s0026-0495(03)00075-1

Genes

GYS1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-12870167-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association of muscle glycogen synthase polymorphism with insulin resistance in type 2 diabetic patients.PMID 12870167Read ↗

A missense mutation of the muscle glycogen synthase gene (M416V) is associated with insulin resistance in the Japanese population.Semantic proximity Read ↗

Association of GYS1 and beta(3)-AR gene with postprandial hyperglycemia and serum uric acid in type 2 diabetes mellitus.Semantic proximity Read ↗

Association of the glycogen synthase locus on 19q13 with NIDDM in Pima Indians.Semantic proximity Read ↗

New variants in the glycogen synthase gene (Gln71His, Met416Val) in patients with NIDDM from eastern Finland.Semantic proximity Read ↗

The stimulation-induced increase in skeletal muscle glycogen synthase content is impaired in carriers of the glycogen synthase XbaI gene polymorphism.Semantic proximity Read ↗

Asp905Tyr polymorphism of the gene for the skeletal muscle-specific glycogen-targeting subunit of protein phosphatase 1 in NIDDM.Semantic proximity Read ↗

Insulin sensitivity is not affected by mutation of codon 972 of the human IRS-1 gene.Semantic proximity Read ↗

Impact of the Xba1-polymorphism of the human muscle glycogen synthase gene on parameters of the insulin resistance syndrome in a Danish twin population.Semantic proximity Read ↗

Molecular and functional characterization of glycogen synthase in the porcine satellite cells under insulin treatment.Semantic proximity Read ↗

Variation in GYS1 interacts with exercise and gender to predict cardiovascular mortality.Semantic proximity Read ↗

Polymorphism of the glycogen synthase gene and non-insulin-dependent diabetes mellitus in the Russian population.Semantic proximity Read ↗

A widespread amino acid polymorphism at codon 905 of the glycogen-associated regulatory subunit of protein phosphatase-1 is associated with insulin resistance and hypersecretion of insulin.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.